Softness, strength and self-repair in intermediate filament networks
نویسندگان
چکیده
منابع مشابه
Softness, strength and self-repair in intermediate filament networks.
One cellular function of intermediate filaments is to provide cells with compliance to small deformations while strengthening them when large stresses are applied. How IFs accomplish this mechanical role is revealed by recent studies of the elastic properties of single IF protein polymers and by viscoelastic characterization of the networks they form. IFs are unique among cytoskeletal filaments...
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Intermediate filaments are common structural elements found in abundance in all metazoan cells, where they form networks that contribute to the elasticity. Here, we report measurements of the linear and nonlinear viscoelasticity of networks of two distinct intermediate filaments, vimentin and neurofilaments. Both exhibit predominantly elastic behavior with strong nonlinear strain stiffening. We...
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ژورنال
عنوان ژورنال: Experimental Cell Research
سال: 2007
ISSN: 0014-4827
DOI: 10.1016/j.yexcr.2007.04.025